IDO Antibody [ID 177]

Hersteller ProSci
Kategorie
Typ Antibody Primary
Specific against Human
Clon ID 177
Isotype IgG1 kappa
Format Liquid
Applikationen WB, ELISA
Menge 100 ug
Host Mouse
ArtNr 36-036
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Immunogen
Recombinant human IDO.
Tested Applications
ELISA: (direct or indirect: 1:2, 000-1:10, 000). Western blot: (1:2, 000-1:5, 000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). Optimal conditions should be determined individually for each application.
Specificity
Recognizes human IDO. Detects a band of ca.45kDa by Western blot. Other species not tested.
Conjugate
Unconjugated
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration
1 mg/ml
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
NCBI Official Symbol
IDO1
Accession #
4504577
Protein GI #
NP_002155.1
NCBI Gene ID
3620
User Note
Optimal dilutions for each application to be determined by the researcher.
NCBI Official Full Name
indoleamine 2, 3-dioxygenase 1
NCBI Organism
Homo sapiens
Swissprot
P14902
Background
IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.

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Menge: 100 ug
Lieferbar: In stock
Listenpreis: 422,12 €
Preis: 422,12 €
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