GITR Antibody [MGIT 07]

Hersteller ProSci
Kategorie
Typ Antibody Primary
Specific against Mouse
Clon MGIT 07
Isotype IgG2a kappa
Format Liquid
Applikationen WB, ELISA
Menge 100 ug
Host Rat
ArtNr 36-007
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Background
GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via the TRAF2/NIK pathway.
Research are
Cancer, Immunology
Alias
Tumor Necrosis Factor Receptor Superfamily Member 18, Activation-inducible TNFR Family Receptor, Glucocorticoid-induced TNFR-related Protein, CD357, TNFRSF18, AITR
Conjugate
Unconjugated
Specificity
Recognizes mouse GITR. Detects a band of ~40kDa by Western blot. Does not cross-react with human GITR.
Immunogen
Recombinant mouse GITR.
Application notes
ELISA: (direct and indirect: 1:5, 000-1:10, 000). Flow Cytometry: (1:1, 000). Western blot (excellent): (1:2, 000-1:5, 000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature.). Optimal conditions must be determined individually for each application.
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Storage
Stable for at least 1 year after receipt when stored at -20˚ C.
Concentration
1 mg/ml
Protein GI #
13878819
Accession #
O35714
NCBI Gene ID #
21936
NCBI symbol
Tnfrsf18
NCBI full name
tumor necrosis factor receptor superfamily, member 18
NCBI organism
Mus musculus
Swissprot #
O35714

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Menge: 100 ug
Lieferbar: Out of stock
Listenpreis: 422,12 €
Preis: 422,12 €
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