Vergleich

RIG-1 Antibody

Hersteller ProSci
Typ Antibody Primary
Specific against other
Isotype IgG
Applikationen E, WB, IHC
Menge 1 mg
Host Rabbit
ArtNr 3953-1
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
BACKGROUND
RIG-1 Antibody: The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the cytoplasmic helicase retinoic acid inducible gene protein 1 (RIG-1) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. Unlike TLR3 however, RIG-1 activates the kinases TBK1 and IKKε, through the adaptor protein IPS-1. These kinases then phosphorylate the transcription factors IRF-3 and IRF-7 which are essential for the expression of type-I interferons. RIG-1 is required for the production of interferons in response to RNA viruses including paramyxoviruses, influenza virus, and Japanese encephalitis virus.
BY RESEARCH AREA
Infectious Disease
CONJUGATE
None
PURIFICATION
RIG-1 Antibody is affinity chromatography purified via peptide column.
CLONALITY
This is a polyclonal RIG-1 Antibody.
IMMUNOGEN
RIG-1 antibody was raised against human GST-tagged RIG-1 protein.
TESTED APPLICATION
E, WB, IHC
BUFFER
RIG-1 Antibody is supplied in PBS containing 0.02% sodium azide.
USER NOTE
Optimal dilutions for each application to be determined by the researcher.
STORAGE CONDITIONS
RIG-1 antibody can be stored at 4C for three months and -20C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
POSITIVE CONTROL 1
Cat. No. 1285 - C2C12 Cell Lysate
POSITIVE CONTROL 2
Cat. No. 1301 - Human Heart Tissue Lysate
SPECIES REACTIVITY
H, M, R
PROTEIN GI #
81170421
ACCESSION #
O95786
DISCLAIMER
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
PHYSICAL STATE
Liquid
CONCENTRATION
1 mg/mL
NCBI GENE ID #
23586
NCBI OFFICIAL SYMBOL
DDX58
NCBI OFFICIAL FULL NAME
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
NCBI ORGANISM
Homo sapiens

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Menge: 1 mg
Lieferbar: In stock
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