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Rabbit anti-RBP4 (C-term.) [+Biotin]

Rabbit anti-RBP4 (C-term.) [+Biotin]

Hersteller	Raybiotech
Kategorie	Antibodies ELISA Primary Antibodies
Typ	Antibody
Specific against	Human
Isotype	IgG
Format	Supplied as lyophilized purified antibody. The antibody is stable for at least one year from the data of receipt when stored at -20C to -70C. Reconstituted antibody (suggesting with sterile PBS) can also be aliquotted and stored frozen at -20C to -70C in
Applikationen	ELISA
Menge	50 ug
Host	Rabbit
ArtNr	RB-08-0032B-50
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Target Name	RBP4 (C-term.)
Accession Number	NM_006744
Conjugate/Tag/Label	Biotin
Application notes:	ELISA (recommended work dilution= 1:10, 000-20, 000 (at least detecting 2-5 ng/ml)), Western Blotting (recommended work dilution= 1:1000-5000(at least)), Enzyme Immunoassay (EIA)
Product Description	Retinol-binding protein 4 (RBP4) is a small transport protein (ca. 23 kDa) and belongs to the lipocalin family with diverse functions. It is the specific carrier protein for retinol (vitamin A alcohol) in the serum. It delivers retinol from the liver stores to the peripheral tissues. In human plasma, the RBPretinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. Recently, RBP4 was known to be one of adipokine secreted by adipocytes and relate to insulin resistance in the AG4KO mouse model. RBP4 may contribute to pathogenesis of type 2 diabetes. Yang et al. demonstrated that serum RBP4 levels are elevated in patients with obesity and type 2 diabetes.
Immunogen	Immunogen was synthetic peptide derived from human Retinol-binding protein 4. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography.

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