Recombinant Human FOLLISTATIN

Hersteller Raybiotech
Kategorie
Typ Proteins
Specific against Human
Menge 20 ug
ArtNr 229-20184
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Short Description
Purified recombinant follistatin expressed in E. coli.
Introduction
Follistatin (FST) is a single-chain glycosylated secreted protein of gonadal origin, originally identified as an antagonist of activin and suppressor of follicle stimulating hormone (FSH) synthesis/secretion. FST is a key regulator in development and regeneration processes, through interaction with members of the transforming growth factor beta (TGF-beta) superfamily, such as bone morphogenetic proteins (BMPs) -2, -4 and -7, myostatin and growth differentiation factor 9 (GDF-9).

This product's activity is measured by by its ability to neutralise the inhibitory effect of Activin A on murine MPC-11 cells. It has a typical ED50 of 0.1 to 0.4 ug/ml in the presence of 7.5ng/ml Activin A.
Protein Name
FOLLISTATIN
Molecular Weight (kDa)
31.5kD (288 amino acid residues)
Purity
>95% by SDS PAGE/HPLC analysis
Concentration
Total protein concentration ca.0.1 mg/ml after reconstitution
Preservative
None present
Endotoxin Level
<1EU/ug
Buffers
Phosphate buffered saline
Protein Type
Recombinant Protein
Recommended Applications
ELISA (0.2-0.4ng/well), Functional Assays (0.1-0.4ug/ml)
Biological activity
Determined by its ability to neutralize Activin A inhibitory effect of murine MPC-11 cells. The expected ED50 is 0.1-0.4 µ g/ml in the presence of 7.5 ng/ml Activin A.
Reconstitution
Reconstitute with 200ul distilled water.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommends that the vial is gently mixed after reconstitution.
Storage/stability
Prior to reconstitution store at +4° C.
After reconstitution store at -20° C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution.
Menge: 20 ug
Lieferbar: Out of stock
Listenpreis: 559,08 €
Preis: 559,08 €
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