Recombinant Human CD54

Hersteller Raybiotech
Kategorie
Typ Proteins
Specific against Human
Menge 50 ug
ArtNr 229-20223
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Short Description
Purified recombinant CD54 expressed in CHO cells
Introduction
CD54, otherwise known as ICAM-1, is a widely expressed type I integral membrane glycoprotein and member of the immunoglobulin superfamily, which acts as a ligand for the leukocyte integrin LFA-1 (CD11a/CD18) and Mac-1 integrins, and is the major receptor for human rhinovirus. CD54 is highly expressed on activated endothelial cells and plays a role in transendothelial cell migration to sites of acute inflammation, functioning primarily as an adhesion molecule between endothelial cells and leucocytes, following injury or stress. Levels of soluble CD54 in serum, can be potentially used as an indication of infection, inflammation and certain tumours, and as a target for immunosuppression in transplantation.
Protein Name
CD54
Molecular Weight (kDa)
49.5kD (453 amino acid residues)
Purity
>98% by SDS PAGE and HPLC analysis
Formulation
10mM Sodium Phosphate
Concentration
ca.0.1mg/ml after reconstitution
Preservative
None present
Endotoxin Level
<1EU/ug
Protein Type
Recombinant Protein
Recommended Applications
ELISA (0.2-0.4ng/well), Functional Assays, Western Blotting (1.5-3.0ng/lane)
Biological activity
CD54 supported the adhesion of more than 50% PMA-stimulated HSB2 cells to plates coated at a CD54 concentration of 25ng/ml.
Reconstitution
Reconstitute with 0.5ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommends that the vial is gently mixed after reconstitution.
Storage/stability
Prior to reconstitution store at +4° C.
After reconstitution store at -20° C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution.

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Menge: 50 ug
Lieferbar: In stock
Listenpreis: 540,00 €
Preis: 540,00 €
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