Recombinant Rat LEPTIN

Hersteller Raybiotech
Kategorie
Typ Proteins
Specific against Rat
Menge 1 mg
ArtNr 229-20330
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Short Description
Purified recombinant leptin expressd in E.coli
Introduction
Leptin is a major adipose-derived hormone and member of the leptin family, which plays a key role in appetite control and the regulation of energy expenditure, and signals through binding to the obesity receptor (OB-R) in the hypothalamus.

Leptin is a recognised marker of obesity and human studies have shown a correlation between circulating levels of leptin and body fat mass, and defects in leptin production result in severe obesity. Regulators of leptin expression include insulin, cortisol, cAMP and thiazolidinediones.
Protein Name
LEPTIN
Molecular Weight (kDa)
16.2kD (147 amino acid residues)
Purity
>98% by SDS PAGE and HPLC analysis
Concentration
ca.1.0mg/ml
Preservative
None present
Endotoxin Level
<1EU/ug
Protein Type
Recombinant Protein
Recommended Applications
Functional Assays
Biological activity
Determined by an in vivo assay using the ob/ob mouse obesity model and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5µ g leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline-treated controls.
Reconstitution
Reconstitute with 1ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommends that the vial is gently mixed after reconstitution.
Storage/stability
Prior to reconstitution store at +4° C.
After reconstitution store at -20° C .
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution.
Menge: 1 mg
Lieferbar: Out of stock
Listenpreis: 559,08 €
Preis: 559,08 €
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