Antibodies

Anti-PPARGC1A antibody

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204,00 €
Zzgl. MwSt.
Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Rat
Isotype IgG
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ114227-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
Q9UBK2
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Gene ID
Gene symbol
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 700 to the C-terminus of human PPARGC1A (NP_037393. 1).
Short Description
Rabbit polyclonal against PPARGC1A
Tissue specificity
Heart, skeletal muscle, liver and kidney. Expressed at lower levels in brain and pancreas and at very low levels in the intestine and white adipose tissue. In skeletal muscle, levels were lower in obese than in lean subjects and fasting induced a 2-fold increase in levels in the skeletal muscle in obese subjects.
Cellular localization
Isoform 1: Nucleus
Nucleus
Pml Body
Isoform B4: Nucleus
Isoform B4-8a: Cytoplasm
Isoform B5: Nucleus
Isoform 9: Nucleus
Molecular weight
Calculated: 14kDa/30kDa/31kDa/33kDa/77kDa/89kDa/91kDa. Observed: 115kDa/120kDa
Dilution range
WB 1:500-1:2000
Alternative names
Anti-Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-Alpha antibody
Anti-Pgc-1-Alpha antibody
Anti-Ppar-Gamma Coactivator 1-Alpha antibody
Anti-Ppargc-1-Alpha antibody
Anti-Ligand Effect Modulator 6 antibody
Anti-PPARGC1A LEM6 PGC1 PGC1A PPARGC1 antibody
Protein name
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-Alpha
Pgc-1-Alpha
Ppar-Gamma Coactivator 1-Alpha
Ppargc-1-Alpha
Ligand Effect Modulator 6
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 204,00 €
Preis: 204,00 €
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