Antibodies

Anti-PPARGC1A Antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody
Specific against Human, Mouse, Rat
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ114227-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Description
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Short Description
Rabbit polyclonal to PPARGC1A
Alternative names
PPARGC1A antibody
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha antibody
PGC-1-alpha antibody
PPAR-gamma coactivator 1-alpha antibody
PPARGC-1-alpha antibody
Ligand effect modulator 6 antibody
PPARGC1A antibody
LEM6 antibody
PGC1 antibody
PGC1A antibody
PPARGC1 antibody
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
WB 1:500 - 1:2000
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene id
Gene symbol
Immunogen
A synthetic peptide of human PPARGC1A
Iso type
IgG
Molecular weight
91.027 kDa
Note
For Research Use Only (RUO).
Purification
Affinity purification
Storage instruction
Store at -20C. Avoid freeze / thaw cycles.
Swiss prot key
Tissue specificity
Heart, skeletal muscle, liver and kidney, Expressed at lower levels in brain and pancreas and at very low levels in the intestine and white adipose tissue, In skeletal muscle, levels were lower in obese than in lean subjects and fasting induced a 2-fold increase in levels in the skeletal muscle in obese subjects
Uniprot id
Q9UBK2

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 235,71 €
Preis: 235,71 €
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