Antibodies

Anti-SPTA1 antibody

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204,00 €
Zzgl. MwSt.
Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Rat
Isotype IgG
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ114233-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
P02549
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.
Gene ID
Gene symbol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 940-1160 of human SPTA1 (NP_003117. 2).
Short Description
Rabbit polyclonal against SPTA1
Cellular localization
Cytoplasm
Cytoskeleton
Cell Cortex
Molecular weight
Calculated: 279kDa/280kDa. Observed: 300kDa
Dilution range
WB 1:500-1:2000
Alternative names
Anti-Spectrin Alpha Chain-Erythrocytic 1 antibody
Anti-Erythroid Alpha-Spectrin antibody
Anti-SPTA1 SPTA antibody
Protein name
Spectrin Alpha Chain-Erythrocytic 1
Erythroid Alpha-Spectrin
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 204,00 €
Preis: 204,00 €
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