Antibodies

Anti-SPTA1 Antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody
Specific against Human, Mouse, Rat
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ114233-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Description
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.
Short Description
Rabbit polyclonal to SPTA1
Alternative names
SPTA1 antibody
Spectrin alpha chain antibody
erythrocytic 1 antibody
Erythroid alpha-spectrin antibody
SPTA1 antibody
SPTA antibody
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
WB 1:500 - 1:2000
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene id
Gene symbol
Immunogen
Recombinant protein of human SPTA1
Iso type
IgG
Molecular weight
280.014 kDa
Note
For Research Use Only (RUO).
Purification
Affinity purification
Storage instruction
Store at -20C. Avoid freeze / thaw cycles.
Swiss prot key
Uniprot id
P02549

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 235,71 €
Preis: 235,71 €
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