Anti-ATP1B1 antibody

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Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Rat
Isotype IgG
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ114278-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
P05026
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+-ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.
Gene ID
481
Gene symbol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 65-240 of human ATP1B1 (NP_001668. 1).
Short Description
Rabbit polyclonal against ATP1B1
Tissue specificity
Found in most tissues.
Cellular localization
Cell Membrane
Single-Pass Type Ii Membrane Protein
Sarcolemma
Colocalizes With Obscn At The Intercalated Disk And Sarcolemma In Cardiomyocytes
Localizes In Long Striations At The Level Of Z And M Lines
Molecular weight
Calculated: 34kDa/35kDa. Observed: 50kDa
Dilution range
WB 1:500-1:2000
Alternative names
Anti-Sodium/Potassium-Transporting Atpase Subunit Beta-1 antibody
Anti-Sodium/Potassium-Dependent Atpase Subunit Beta-1 antibody
Anti-ATP1B1 ATP1B antibody
Protein name
Sodium/Potassium-Transporting Atpase Subunit Beta-1
Sodium/Potassium-Dependent Atpase Subunit Beta-1
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 204,00 €
Preis: 204,00 €
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