Hersteller |
St John's Laboratory
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Isotype |
IgG |
Applikationen |
WB |
Menge |
50ul |
Host |
Rabbit |
ArtNr |
STJ114278-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
P05026 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+-ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 65-240 of human ATP1B1 (NP_001668. 1). |
Short Description |
Rabbit polyclonal against ATP1B1 |
Tissue specificity |
Found in most tissues. |
Cellular localization |
Cell MembraneSingle-Pass Type Ii Membrane ProteinSarcolemmaColocalizes With Obscn At The Intercalated Disk And Sarcolemma In CardiomyocytesLocalizes In Long Striations At The Level Of Z And M Lines |
Molecular weight |
Calculated: 34kDa/35kDa. Observed: 50kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Sodium/Potassium-Transporting Atpase Subunit Beta-1 antibodyAnti-Sodium/Potassium-Dependent Atpase Subunit Beta-1 antibodyAnti-ATP1B1 ATP1B antibody |
Protein name |
Sodium/Potassium-Transporting Atpase Subunit Beta-1Sodium/Potassium-Dependent Atpase Subunit Beta-1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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