Vergleich

Anti-NTRK2 antibody (41-433) (STJ114207)

Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse
Isotype IgG
Applikationen WB
Menge 50 ul
Host Rabbit
ArtNr STJ114207-50
Targets MYH14;;NTF3;;NTRK1;;NTRK2;;TRK-CTT2-3
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
Q16620
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
Gene ID
Gene symbol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 41-433 of human NTRK2 (NP_001007098. 1).
Short Description
Rabbit polyclonal against NTRK2
Tissue specificity
Isoform TrkB is expressed in the central and peripheral nervous system. In the central nervous system (CNS), expression is observed in the cerebral cortex, hippocampus, thalamus, choroid plexus, granular layer of the cerebellum, brain stem, and spinal cord. In the peripheral nervous system, it is expressed in many cranial ganglia, the ophthalmic nerve, the vestibular system, multiple facial structures, the submaxillary glands, and dorsal root ganglia. Isoform TrkB-T1 is mainly expressed in the brain but also detected in other tissues including pancreas, kidney and heart. Isoform TrkB-T-Shc is predominantly expressed in the brain.
Cellular localization
Cell Membrane
Single-Pass Type I Membrane Protein
Endosome Membrane
Early Endosome Membrane
Cell Projection
Axon
Dendrite
Cytoplasm
Perinuclear Region
Cell Junction
Synapse
Postsynaptic Density
Internalized To Endosomes Upon Ligand-Binding
Molecular weight
Calculated: 35kDa/53kDa/59kDa/60kDa/81kDa/91kDa/93kDa. Observed: 105kDa
Dilution range
WB 1:500-1:2000
Alternative names
Anti-Bdnf/Nt-3 Growth Factors Receptor antibody
Anti-Gp145-Trkb antibody
Anti-Trk-B antibody
Anti-Neurotrophic Tyrosine Kinase Receptor Type 2 antibody
Anti-Trkb Tyrosine Kinase antibody
Anti-Tropomyosin-Related Kinase B antibody
Anti-NTRK2 TRKB antibody
Protein name
Bdnf/Nt-3 Growth Factors Receptor
Gp145-Trkb
Trk-B
Neurotrophic Tyrosine Kinase Receptor Type 2
Trkb Tyrosine Kinase
Tropomyosin-Related Kinase B
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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Lieferung vsl. bis 25.04.2024 

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