Anti-NTRK2 Antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody
Specific against Human, Mouse
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ114207-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Description
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
Short Description
Rabbit polyclonal to NTRK2
Alternative names
NTRK2 antibody
BDNF/NT-3 growth factors receptor antibody
NTRK2 antibody
TRKB antibody
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
WB 1:500 - 1:2000
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene id
Gene symbol
Immunogen
Recombinant protein of human NTRK2
Iso type
IgG
Molecular weight
91.999 kDa
Note
For Research Use Only (RUO).
Purification
Affinity purification
Storage instruction
Store at -20C. Avoid freeze / thaw cycles.
Swiss prot key
Tissue specificity
Isoform TrkB is expressed in the central and peripheral nervous system, In the central nervous system (CNS), expression is observed in the cerebral cortex, hippocampus, thalamus, choroid plexus, granular layer of the cerebellum, brain stem, and spinal cord, In the peripheral nervous system, it is expressed in many cranial ganglia, the ophthalmic nerve, the vestibular system, multiple facial structures, the submaxillary glands, and dorsal root ganglia, Isoform TrkB-T1 is mainly expressed in the brain but also detected in other tissues including pancreas, kidney and heart, Isoform TrkB-T-Shc is predominantly expressed in the brain
Uniprot id
Q16620

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 235,71 €
Preis: 235,71 €
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