Antibodies

Anti-STAT5B Antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody
Specific against Human, Mouse
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ114234-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Description
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
Short Description
Rabbit polyclonal to STAT5B
Alternative names
STAT5B antibody
Signal transducer and activator of transcription 5B antibody
STAT5B antibody
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
WB 1:500 - 1:2000
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene id
Gene symbol
Immunogen
A synthetic peptide of human STAT5B
Iso type
IgG
Molecular weight
89.866 kDa
Note
For Research Use Only (RUO).
Purification
Affinity purification
Storage instruction
Store at -20C. Avoid freeze / thaw cycles.
Swiss prot key
Uniprot id
P51692

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 235,71 €
Preis: 235,71 €
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