Hersteller |
St John's Laboratory
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human |
Isotype |
IgG |
Applikationen |
WB |
Menge |
50ul |
Host |
Rabbit |
ArtNr |
STJ114200-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q10589 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 49-161 of human BST2 (NP_004326. 1). |
Short Description |
Rabbit polyclonal against BST2 |
Tissue specificity |
Predominantly expressed in liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal muscle and brain. Overexpressed in multiple myeloma cells. Highly expressed during B-cell development, from pro-B precursors to plasma cells. Highly expressed on T-cells, monocytes, NK cells and dendritic cells (at protein level). |
Cellular localization |
Golgi ApparatusTrans-Golgi NetworkCell MembraneSingle-Pass Type Ii Membrane ProteinLipid-AnchorGpi-AnchorLate EndosomeMembrane RaftCytoplasmApical Cell MembraneShuttles Between The Cell MembraneWhere It Is Present Predominantly In Membrane/Lipid RaftsAnd The Trans-Golgi NetworkHiv-1 Vpu And Hiv-2 Env Can Target It To The Trans-Golgi Network Thus Sequestering It Away From Virus Assembly Sites On The Cell MembraneTargeted To Late Endosomes Upon Kshv Infection And Subsequent UbiquitinationForms A Complex With Mmp14 And Localizes To The Cytoplasm |
Molecular weight |
Calculated: 18kDa/19kDa. Observed: 35-40kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Bone Marrow Stromal Antigen 2 antibodyAnti-Bst-2 antibodyAnti-Hm1.24 Antigen antibodyAnti-Tetherin antibodyAnti-Cd Antigen Cd317 antibodyAnti-BST2 antibody |
Protein name |
Bone Marrow Stromal Antigen 2Bst-2Hm1.24 AntigenTetherinCd Antigen Cd317 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
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