Anti-CD59 antibody

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Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human
Isotype IgG
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ114286-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
P13987
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Gene ID
966
Gene symbol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 26-128 of human CD59 (NP_001120695. 1).
Short Description
Rabbit polyclonal against CD59
Cellular localization
Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Soluble Form Found In A Number Of Tissues
Molecular weight
Calculated: 14kDa. Observed: 14kDa
Dilution range
WB 1:500-1:2000
Alternative names
Anti-Cd59 Glycoprotein antibody
Anti-1f5 Antigen antibody
Anti-20 Kda Homologous Restriction Factor antibody
Anti-Hrf-20 antibody
Anti-Hrf20 antibody
Anti-Mac-Inhibitory Protein antibody
Anti-Mac-Ip antibody
Anti-Mem43 Antigen antibody
Anti-Membrane Attack Complex Inhibition Factor antibody
Anti-Macif antibody
Anti-Membrane Inhibitor Of Reactive Lysis antibody
Anti-Mirl antibody
Anti-Protectin antibody
Anti-Cd Antigen Cd59 antibody
Anti-CD59 MIC11 MIN1 MIN2 MIN3 MSK21 antibody
Protein name
Cd59 Glycoprotein
1f5 Antigen
20 Kda Homologous Restriction Factor
Hrf-20
Hrf20
Mac-Inhibitory Protein
Mac-Ip
Mem43 Antigen
Membrane Attack Complex Inhibition Factor
Macif
Membrane Inhibitor Of Reactive Lysis
Mirl
Protectin
Cd Antigen Cd59
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 204,00 €
Preis: 204,00 €
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