Anti-CD59 Antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody
Specific against Human
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ114286-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Description
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Short Description
Rabbit polyclonal to CD59
Alternative names
CD59 antibody
CD59 glycoprotein antibody
1F5 antigen antibody
20 kDa homologous restriction factor antibody
HRF-20 antibody
HRF20 antibody
MAC-inhibitory protein antibody
MAC-IP antibody
MEM43 antigen antibody
Membrane attack complex inhibition factor antibody
MACIF antibody
Membrane inhibitor of reactive lysis antibody
MIRL antibody
Protectin antibody
CD antigen CD59 antibody
CD59 antibody
MIC11 antibody
MIN1 antibody
MIN2 antibody
MIN3 antibody
MSK21 antibody
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
WB 1:500 - 1:2000
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene id
Gene symbol
Immunogen
Recombinant protein of human CD59
Iso type
IgG
Molecular weight
14.177 kDa
Note
For Research Use Only (RUO).
Purification
Affinity purification
Storage instruction
Store at -20C. Avoid freeze / thaw cycles.
Swiss prot key
Uniprot id
P13987

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 235,71 €
Preis: 235,71 €
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