Vergleich

Anti-CFH antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human
Isotype IgG
Applikationen WB
Menge 100ul
Host Rabbit
ArtNr STJ115641-100
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
P08603
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
Gene symbol
CFH
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 270-445 of human CFH (NP_001014975. 1).
Short Description
Rabbit polyclonal against CFH
Tissue specificity
Expressed in the retinal pigment epithelium (at protein level). CFH is one of the most abundant complement components in blood where the liver is the major source of CFH protein in vivo. in addition, CFH is secreted by additional cell types including monocytes, fibroblasts, or endothelial cells.
Cellular localization
Secreted
Molecular weight
Calculated: 51kDa/139kDa. Observed: 139kDa
Dilution range
WB 1:500-1:2000
Alternative names
Anti-Complement Factor H antibody
Anti-H Factor 1 antibody
Anti-CFH HF HF1 HF2 antibody
Protein name
Complement Factor H
H Factor 1
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 09.05.2024 

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen