Antibodies

U2AF1

Manufacturer Abclonal
Category Products / Antibody
Type Antibody Polyclonal
Specific against Human, Mouse, Rat
Isotype IgG
Applications WB, IF, IHC
Amount 100ug
Host Rabbit
ArtNr A1046-100ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Available
Background
U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1, synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.
Gene Symbol
U2AF1
Gene Template
Human
GeneID
7307
Route
Recombinant Protein
SWISS
Q01081
Protein MW (aa)
28kDa
Synonyms
U2AF1, DKFZp313J1712, FP793, RN, RNU2AF1, U2AF35, U2AFBP,
Purity
Affinity purification
Storage Buffer
Store at -20C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Illustration
Western blot analysis of extracts of various cells, using U2AF1 antibody. Immunohistochemistry of paraffin-embedded rat Intestine using U2AF1 antibody at dilution of 1:200 (400x lens). Immunohistochemistry of paraffin-embedded human oophoroma using U2AF1 antibody at dilution of 1:200 (400x lens). Immunohistochemistry of paraffin-embedded mouse liver using U2AF1 antibody at dilution of 1:200 (400x lens).
Amount: 100ug
Available: In stock
Listprice: €263.00
Price: €263.00
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Instruction sheet

A1046-100ug.pdf