Antibodies

IL1R2

Manufacturer Abclonal
Category Products / Antibody
Type Antibody Polyclonal
Specific against Human
Isotype IgG
Applications WB, IHC
Amount 100ug
Host Rabbit
ArtNr A1899-100ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Available
Background
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.
Gene Symbol
IL1R2
Gene Template
Human
GeneID
7850
Route
Recombinant Protein
SWISS
P27930
Protein MW (aa)
45kDa
Synonyms
IL1RB, CD121b, IL1R2c, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2,
Purity
Affinity purification
Storage Buffer
Store at -20C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Illustration
Western blot analysis of extracts of various cell lines, using IL1R2 antibody. Immunohistochemistry of paraffin-embedded human thyroid cancer using IL1R2 antibody at dilution of 1:100 (x400 lens). Immunohistochemistry of paraffin-embedded human endometrial cancer using IL1R2 antibody at dilution of 1:100 (x400 lens).
Amount: 100ug
Available: In stock
Listprice: €263.00
Price: €263.00
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Instruction sheet

A1899-100ug.pdf