Antibodies

GRM3

Manufacturer Abclonal
Category Products / Antibody
Type Antibody Polyclonal
Specific against Human, Mouse, Rat
Isotype IgG
Applications WB, IHC
Amount 100ug
Host Rabbit
ArtNr A2538-100ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Available
Background
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Gene Symbol
GRM3
Gene Template
Human
GeneID
2913
Route
Recombinant Protein
SWISS
Q14832
Protein MW (aa)
98kDa
Synonyms
GLUR3, mGlu3, GPRC1C, MGLUR3,
Purity
Affinity purification
Storage Buffer
Store at -20C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Illustration
Western blot analysis of extracts of various cell lines, using GRM3 antibody. Immunofluorescence analysis of U2OS cell using GRM3 antibody. Blue: DAPI for nuclear staining
Amount: 100ug
Available: In stock
Listprice: €263.00
Price: €263.00
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Instruction sheet

A2538-100ug.pdf