Antibodies

CCND2

Manufacturer Abclonal
Category Products / Antibody
Type Antibody Polyclonal
Specific against Human
Isotype IgG
Applications WB
Amount 200ug
Host Rabbit
ArtNr A2892-200ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Available
Background
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.
Gene Symbol
CCND2
Gene Template
Human
GeneID
894
Route
Synthetic Peptide
SWISS
P30279
Protein MW (aa)
33kDa
Synonyms
KIAK0002, MGC102758,
Purity
Affinity purification
Storage Buffer
Store at -20C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions
WB 1:500 - 1:2000
Illustration
Western blot analysis of extracts of 231 cell line, using CCND2 antibody.
Amount: 200ug
Available: In stock
Listprice: €404.00
Price: €404.00
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Instruction sheet

A2892-200ug.pdf