Antibodies

PSMC6

Manufacturer Abclonal
Category Products / Antibody
Type Antibody Polyclonal
Specific against Human, Mouse, Rat
Isotype IgG
Applications WB, IHC
Amount 50ug
Host Rabbit
ArtNr A5377-50ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Available
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
Gene Symbol
PSMC6
Gene Template
Human
GeneID
5706
Route
Recombinant Protein
SWISS
P62333
Protein MW (aa)
44kDa
Synonyms
P44, p42, SUG2, CADP44,
Purity
Affinity purification
Storage Buffer
Store at -20C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Illustration
Western blot analysis of extracts of various cell lines, using PSMC6 antibody. Immunohistochemistry of paraffin-embedded human kidney using PSMC6 antibody at dilution of 1:100 (x400 lens).
Amount: 50ug
Available: In stock
Listprice: €198.00
Price: €198.00
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Instruction sheet

A5377-50ug.pdf