Antibodies

RANTES

Manufacturer Abclonal
Category Products / Antibody
Type Antibody Polyclonal
Specific against Human
Isotype IgG
Applications WB, IHC
Amount 200ug
Host Rabbit
ArtNr A5630-200ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Available
Background
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
Gene Symbol
CCL5
Gene Template
Human
GeneID
6352
Route
Recombinant Protein
SWISS
P13501
Protein MW (aa)
9kDa
Synonyms
SISd, eoCP, SCYA5, RANTES, TCP228, D17S136E, SIS-delta,
Purity
Affinity purification
Storage Buffer
Store at -20C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Illustration
Western blot analysis of extracts of various cell lines, using CCL5 antibody.
Amount: 200ug
Available: In stock
Listprice: €404.00
Price: €404.00
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Instruction sheet

A5630-200ug.pdf