Antibodies

CXCR3

Manufacturer Abclonal
Category Products / Antibody
Type Antibody Polyclonal
Specific against Human, Mouse, Rat
Isotype IgG
Applications WB, IHC
Amount 50ug
Host Rabbit
ArtNr A2939-50ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Available
Background
The neuronal growth-associated protein GAP43 is also known as neuromodulin, B-50, P-57, F1 and pp46. Deficiency of GAP43 in mice results in death early in the postnatal period. GAP43 is one of the main substrates for protein kinase C in the brain. GAP43 is an intracellular growth-associated protein that appears to assist neuronal pathfinding and branching during development and regeneration, and may contribute to presynaptic membrane changes in the adult, leading to the neurotransmitter release, endocytosis and synaptic vesicle recycling, long-term potentiation, spatial memory formation, and learning. The predicated molecular weight of about 25 kDa is much lower than the apparent observed molecular weight of 43 kDa on SDS-PAGE gels, and this occurs because the highly charged nature of GAP43 causes it to bind less than the average amount of SDS per amino acid, and because the protein has an elongated structure.
Gene Symbol
CXCR3
Gene Template
Human
GeneID
2833
Route
Synthetic Peptide
SWISS
P49682
Protein MW (aa)
46kDa
Synonyms
GPR9, MigR, CD182, CD183, Mig-R, CKR-L2, CMKAR3, IP10-R,
Purity
Affinity purification
Storage Buffer
Store at -20C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:100
Illustration
Western blot analysis of extracts of various cell lines, using CXCR3 antibody. Immunohistochemistry of paraffin-embedded human stomach cancer tissue using CXCR3 antibody. Immunohistochemistry of paraffin-embedded human metrocarcinoma using CXCR3 antibody at dilution of 1:200 (400x lens). Immunohistochemistry of paraffin-embedded human kidney cancer using CXCR3 antibody at dilution of 1:200 (400x lens).
Amount: 50ug
Available: In stock
Listprice: €198.00
Price: €198.00
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Instruction sheet

A2939-50ug.pdf