Comparison

CNX-2006 100mg

Item no. A13755-100
Manufacturer Adooq
CASRN 1375465-09-0
Amount 100 mg
Quantity options 1 mg 10 mg 100 mg 10mM x 1mL in DMSO 2 mg 25 mg 5 mg 50 mg
Category
Type Inhibitors
Specific against other
Purity >98%
Smiles COC1=C(C=CC(=C1)NC2CN(C2)CCF)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)C(F)(F)F
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias CNX2006, CNX 2006
Similar products CNX-2006
Available
Storage Conditions
2 years at -20C
Molecular Weight
545, 53
Chemical Name
N-(3-((2-((4-((1-(2-fluoroethyl)azetidin-3-yl)amino)-2-methoxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide
Description
CNX-2006 is a potent, mutant-selective EGFR inhibitor with excellent in vitro activity in cells with activating EGFR mutations, as well as in cells harbouring the T790M mutation. CNX-2006 is the prototype for CO-1686, which is currently in a Phase I clinical trial for the treatment of EGFR-mutant lung cancer.
Solubilty
DMSO

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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