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ATG4A Antibody (OAAB18678)

ATG4A Antibody (OAAB18678)

Item no.	OAAB18678
Manufacturer	AVIVA Systems Biology
Amount	400 ul
Category	Neuroscience Neural Lineage Markers Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Western Blot Autophagy Primary Antibodies Glial Cell Markers
Type	Antibody Monoclonal
Applications	WB
Specific against	other
Host	Mouse
Isotype	IgG2b kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Shipping Temperature	Wet Ice
Gene symbol	ATG4A
Product format	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Clonality	Monoclonal
Purification	This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen	This ATG4A antibody is generated from a mouse immunized with a recombinant protein.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 12/11/2025

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