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GARS Antibody

GARS Antibody

Item no.	PRS-19-658-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Microglia Markers
Type	Antibody Primary
Format	Liquid
Applications	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	GARS
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CMT2D,DSMAV,GlyRS,HMN5,SMAD1,glycine--tRNA ligase,AP-4-A synthetase,Charcot-Marie-Tooth neuropathy 2D,Charcot-Marie-Tooth neuropathy,neuronal type,D,ap4A synthetase,diadenosine tetraphosphate synthetase
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 83kDa
Manufacturer - Research Area	Other
Background	This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.
By Type	Other
Modifications	None
Purification	Affinity purification
Positive Control 1	Jurkat
Positive Control 2	293T
Positive Control 3	U-87MG
Positive Control 4	Raji
Positive Control 5	M21
Positive Control 6	HT-29
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:1000 - 1:4000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 60-370 of human GARS (NP_002038.2).
Clonality	Polyclonal
NCBI Official Name	glycyl-tRNA synthetase
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 12/4/2025

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