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TBL1XR1 Antibody

TBL1XR1 Antibody

Item no.	PRS-23-215-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Neuroscience Neuroinflammation Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	TBL1XR1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	F-box-like/WD repeat-containing protein TBL1XR1,Nuclear receptor corepressor/HDAC3 complex subunit TBLR1,TBL1-related protein 1,Transducin beta-like 1X-related protein 1,TBL1XR1,IRA1,TBLR1
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 60kDa
Manufacturer - Research Area	Cancer, Cell Cycle, Signal Transduction
Background	This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.
By Type	Cancer, Cell Cycle, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	Jurkat
Positive Control 2	HepG2
Positive Control 3	NCI-H460
Positive Control 4	THP-1
Positive Control 5	Mouse brain
Positive Control 6	Mouse spleen
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human TBL1XR1 (NP_078941.2).
Clonality	Polyclonal
NCBI Official Name	F-box-like/WD repeat-containing protein TBL1XR1
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 12/4/2025

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