Comparison

InVivoMab anti-mouse/human VLA-4 (CD49d) (Clone: PS/2)

Manufacturer Bio X Cell
Category
Type Antibody Monoclonal
Specific against Mouse
Clone PS/2
Isotype IgG2b
Applications in vivo
Amount 100mg
Host Rat
Item no. BE0071-100MG
eClass 6.1 32160702
eClass 9.0 42030590
Available
Quantity options
Description
The PS/2 monoclonal antibody reacts with human and mouse VLA-4 alpha chain also known as CD49d and integrin alpha 4. VLA-4 is a 150 kDa glycoprotein belonging to the integrin family that is expressed by many cell types including T and B lymphocytes, monocytes, eosinophils, basophils, mast cells, thymocytes, NK cells, and dendritic cells. Integrin alpha4 associates with integrin beta7 to form integrin alpha4beta7 also known as LPAM-1 as well as integrin beta1 (CD29) to form integrin alpha4beta1 also known as VLA-4. Integrin alpha4 plays roles in adhesion and T cell co-stimulation. Integrin alpha4 ligands include VCAM-1, MAdCAM-1, and fibronectin. The PS/2 antibody is useful for in vivo and in vitro VLA-4 neutralization.
Endotoxin
<2EU/mg (<0.002EU/ug)
Determined by LAL gel clotting assay
Formulation
PBS, pH 6.5
Contains no stabilizers or preservatives
Immunogen
Mouse P815 mast cells
Isotype
Rat IgG2b, kappa
Molecular Weight
150 kDa
Production
Purified from tissue culture supernatant in an animal free facility
Purification
Protein G
Purity
>95%
Determined by SDS-PAGE
RRID
AB_1107657
Recommended InVivoPure Dilution Buffer
InVivoPure pH 6.5 Dilution Buffer(IP0065)
Recommended Isotype Control(s)
InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin(BE0090)
Reported Applications
in vivo VLA-4 neutralization
in vitro VLA-4 neutralization
Flow cytometry
Sterility
0.2 uM filtered
Storage
The antibody solution should be stored at the stock concentration at 4C. Do not freeze.

Note: The presented information and documents (Manual, Product Datasheet and Safety Datasheet) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 100mg
Available: In stock
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