Comparison

InVivoMab anti-mouse PSGL-1 (CD162) (Clone: 4RA10)

Manufacturer Bio X Cell
Category
Type Antibody Monoclonal
Specific against Mouse
Clone 4RA10
Isotype IgG1
Applications in vivo
Amount 100mg
Host Rat
Item no. BE0186-100MG
eClass 6.1 32160702
eClass 9.0 42030590
Available
Quantity options
Description
The 4RA10 monoclonal antibody reacts with mouse P-selectin glycoprotein ligand-1 (PSGL-1) also known as CD162. PSGL-1 is a 230 kDa glycoprotein that is expressed by bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and T lymphocytes. PSGL-1 is a ligand for P-selectin (CD62P) and plays roles in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. The 4RA10 antibody is reported to block the binding of mouse leukocytes to CD62P and CD62L.
Endotoxin
<2EU/mg (<0.002EU/ug)
Determined by LAL gel clotting assay
Formulation
PBS, pH 7.0
Contains no stabilizers or preservatives
Immunogen
Mouse PSGL-1 human IgG1 fusion protein
Isotype
Rat IgG1, kappa
Molecular Weight
150 kDa
Production
Purified from tissue culture supernatant in an animal free facility
Purification
Protein G
Purity
>95%
Determined by SDS-PAGE
RRID
AB_10950305
Recommended InVivoPure Dilution Buffer
InVivoPure pH 7.0 Dilution Buffer(IP0070)
Recommended Isotype Control(s)
InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase(BE0088)
Reported Applications
in vivo PSGL-1 blockade
Immunohistochemistry (frozen)
Sterility
0.2 uM filtered
Storage
The antibody solution should be stored at the stock concentration at 4C. Do not freeze.

Note: The presented information and documents (Manual, Product Datasheet and Safety Datasheet) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 100mg
Available: In stock
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