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Keap1 Antibody

Keap1 Antibody

Item no.	CSB-PA012147LA01MO-50ug
Manufacturer	Cusabio
Amount	50 ug
Quantity options	100 ug 20 ug 50 ug
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Movement Cell Adhesion Adenocarcinoma Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Keap1 antibody,Inrf2 antibody,Kiaa0132Kelch-like ECH-associated protein 1 antibody,Cytosolic inhibitor of Nrf2 antibody,INrf2 antibody
Similar products	Keap1, Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2), Inrf2 Kiaa0132
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB; Recommended dilution: WB:1:500-1:2000
Manufacturer - Targets	Keap1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species	Mouse
Immunogen	Recombinant Mouse Kelch-like ECH-associated protein 1 protein (1-624AA)
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:2000
Background	Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity).
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Others
Antigen Species	Mouse
Antigen	Recombinant Mouse Kelch-like ECH-associated protein 1 protein (1-624AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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CSB-PA012147LA01MO-50ug-datasheet.pdf

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Amount: 50 ug

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Delivery expected until 12/25/2025

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