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Phospho-FOXO3 (Ser253) Antibody

Phospho-FOXO3 (Ser253) Antibody

Item no.	CSB-PA030478
Manufacturer	Cusabio
Amount	100 ul
Category	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Sarcoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AF6q21 antibody,AF6q21 protein antibody,DKFZp781A0677 antibody,FKHR2 antibody,FKHRL 1 antibody,FKHRL1 antibody,FKHRL1P2 antibody,Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1 antibody,Forkhead box O3 antibody,Forkhead box O3A antibody,Forkhead box protein O3 antibody,Forkhead box protein O3A antibody,Forkhead Drosophila homolog of in rhabdomyosarcoma like 1 antibody,Forkhead homolog (rhabdomyosarcoma) like 1 antibody,Forkhead in rhabdomyosarcoma like 1 antibody,Forkhead in rhabdomyosarcoma-like 1 antibody,FOX O3A antibody,FOXO2 antibody,foxo3 antibody,FOXO3_HUMAN antibody,FOXO3A antibody,MGC12739 antibody,MGC31925 antibody
Similar products	FOXO3A, FKHRL1, AF6q21, FKHRL1P2, FOXO2
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200
Manufacturer - Targets	FOXO3
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	AF6q21 antibody, AF6q21 protein antibody, DKFZp781A0677 antibody, FKHR2 antibody, FKHRL 1 antibody, FKHRL1 antibody, FKHRL1P2 antibody, Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1 antibody, Forkhead box O3 antibody, Forkhead box O3A antibody, Forkhead box protein O3 antibody, Forkhead box protein O3A antibody, Forkhead Drosophila homolog of in rhabdomyosarcoma like 1 antibody, Forkhead homolog (rhabdomyosarcoma) like 1 antibody, Forkhead in rhabdomyosarcoma like 1 antibody, Forkhead in rhabdomyosarcoma-like 1 antibody, FOX O3A antibody, FOXO2 antibody, foxo3 antibody, FOXO3_HUMAN antibody, FOXO3A antibody, MGC12739 antibody, MGC31925 antibody
Immunogen Species	Human
Immunogen	Peptide sequence around phosphorylation site of serine 253(A-V-S(p)-M-D) derived from Human FKHRL1.
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:1000 IHC:1:50-1:100 IF:1:100-1:200
Background	, Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation. Lehtinen M.K., Yuan Z., Boag P.R., Yang Y., Villen J., Becker E.B.E., DiBacco S., de la Iglesia N., Gygi S.P., Blackwell T.K., Bonni A.Cell 125:987-1001(2006) , , , , , , , , , , , , , , Morishita D., Katayama R., Sekimizu K., Tsuruo T., Fujita N.Cancer Res. 68:5076-5085(2008) Kress T.R., Cannell I.G., Brenkman A.B., Samans B., Gaestel M., Roepman P., Burgering B.M., Bushell M., Rosenwald A., Eilers M.Mol. Cell 41:445-457(2011) , , , , , , , , , , , , ,
Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Peptide sequence around phosphorylation site of serine 253(A-V-S(p)-M-D) derived from Human FKHRL1.
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 12/25/2025

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