TAF1 Antibody

Polyclonal Antibody

TAF1

BA2R antibody, CCG1 antibody, CCGS antibody, Cell cycle G1 phase defect antibody, Cell cycle gene 1 protein antibody, Complementation of cell cycle block G1 to S antibody, DYT3 antibody, N TAF1 antibody, NSCL2 antibody, OF antibody, p250 antibody, TAF 1 antibody, TAF(II)250 antibody, TAF1 antibody, TAF1 RNA polymerase II TATA box binding protein (TBP) associated factor 250kDa antibody, TAF1_HUMAN antibody, TAF2A antibody, TAFII-250 antibody, TAFII250 antibody, TATA box binding protein (TBP) associated factor RNA polymerase II A 250kD antibody, TBP associated factor 250 kDa antibody, TBP-associated factor 250 kDa antibody, Transcription factor TFIID p250 polypeptide antibody, Transcription initiation factor TFIID 250 kDa subunit antibody, Transcription initiation factor TFIID subunit 1 antibody, XDP antibody

Synthesized peptide derived from internal of human TAF1.

Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Exhibits histone acetyltransferase activity towards histones H3 and H4.

Sekiguchi T., Mol. Cell. Biol. 11:3317-3325(1991).
Ruppert S., Nature 362:175-179(1993).
Nolte D., Proc. Natl. Acad. Sci. U.S.A. 100:10347-10352(2003).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Epigenetics and Nuclear Signaling

Synthesized peptide derived from internal of Human TAF1.