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Phospho-BLM (Thr99) Antibody

Phospho-BLM (Thr99) Antibody

Item no.	CSB-PA188391
Manufacturer	Cusabio
Amount	100 ul
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Blm antibody,BLM_HUMAN antibody,Bloom syndrome antibody,Bloom syndrome protein antibody,Bloom syndrome RecQ helicase like antibody,BS antibody,DNA helicase antibody,DNA helicase RecQ like type 2 antibody,MGC126616 antibody,MGC131618 antibody,MGC131620 antibody,RECQ 2 antibody,RECQ like antibody,RecQ like type 2 antibody,RecQ protein like 3 antibody,RecQ protein-like 3 antibody,RecQ-like type 2 antibody,RecQ2 antibody,RECQL 2 antibody,RECQL 3 antibody,RECQL2 antibody,RECQL3 antibody,type 2 antibody
Similar products	RECQL3, RECQ2, type 2, RecQ protein-like 3, EC 3.6.1
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:100
Manufacturer - Targets	BLM
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	Blm antibody, BLM_HUMAN antibody, Bloom syndrome antibody, Bloom syndrome protein antibody, Bloom syndrome RecQ helicase like antibody, BS antibody, DNA helicase antibody, DNA helicase RecQ like type 2 antibody, MGC126616 antibody, MGC131618 antibody, MGC131620 antibody, RECQ 2 antibody, RECQ like antibody, RecQ like type 2 antibody, RecQ protein like 3 antibody, RecQ protein-like 3 antibody, RecQ-like type 2 antibody, RecQ2 antibody, RECQL 2 antibody, RECQL 3 antibody, RECQL2 antibody, RECQL3 antibody, type 2 antibody
Immunogen Species	Human
Immunogen	Peptide sequence around phosphorylation site of threonine 99 (Q-E-T(p)-Q-R) derived from Human Bloom Syndrome.
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:1000 IHC:1:50-1:100
Background	Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE). Ellis N.A., Cell 83:655-666(1995). Karow J.K., J. Biol. Chem. 272:30611-30614(1997). Pichierri P., EMBO J. 23:3154-3163(2004).
Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Peptide sequence around phosphorylation site of threonine 99 (Q-E-T(p)-Q-R) derived from Human Bloom Syndrome.
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 12/25/2025

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