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EP300/CREBBP Antibody

EP300/CREBBP Antibody

Item no.	CSB-PA265859
Manufacturer	Cusabio
Amount	100 ul
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Sarcoma Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E1A associated protein p300 antibody,E1A binding protein p300 antibody,E1A-associated protein p300 antibody,EP300 antibody,EP300: E1A binding protein p300 antibody,EP300_HUMAN antibody,Histone acetyltransferase p300 antibody,KAT3B antibody,p300 HAT antibody,RSTS2 antibody
Similar products	EP300, CREB-binding protein, P300 transcription coactivator homolog, CREBBP E1A-associated protein p300
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100
Manufacturer - Targets	EP300/CREBBP
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	E1A associated protein p300 antibody, E1A binding protein p300 antibody, E1A-associated protein p300 antibody, EP300 antibody, EP300: E1A binding protein p300 antibody, EP300_HUMAN antibody, Histone acetyltransferase p300 antibody, KAT3B antibody, p300 HAT antibody, RSTS2 antibody
Immunogen Species	Human
Immunogen	Synthesized peptide derived from human P300/CBP.
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:3000 IHC:1:50-1:100
Background	Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Gerd A. Blobel, J. Leukoc. Biol., Apr 2002, 71: 545. Eric Kalkhoven, Hum. Mol. Genet., Feb 2003, 12: 441 - 450. Wei-fang Shen, Mol. Cell. Biol., Nov 2001, 21: 7509 - 7522. Frederick C. Nucifora, Science, Mar 2001, 291: 2423.
Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Synthesized peptide derived from Human P300/CBP.
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 12/25/2025

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