Comparison

Phospho-FOXO1 (Ser319) Antibody

Item no. CSB-PA284263
Manufacturer Cusabio
Amount 100 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias FKH 1 antibody,FKH1 antibody,FKHR antibody,Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma) antibody,Forkhead box O1 antibody,Forkhead box protein O1 antibody,Forkhead box protein O1A antibody,Forkhead in rhabdomyosarcoma antibody,Forkhead,Drosophila,homolog of,in rhabdomyosarcoma antibody,FoxO transcription factor antibody,foxo1 antibody,FOXO1_HUMAN antibody,FOXO1A antibody,OTTHUMP00000018301 antibody
Similar products FOXO1
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200
Manufacturer - Targets
FOXO1
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
FKH 1 antibody, FKH1 antibody, FKHR antibody, Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma) antibody, Forkhead box O1 antibody, Forkhead box protein O1 antibody, Forkhead box protein O1A antibody, Forkhead in rhabdomyosarcoma antibody, Forkhead, Drosophila, homolog of, in rhabdomyosarcoma antibody, FoxO transcription factor antibody, foxo1 antibody, FOXO1_HUMAN antibody, FOXO1A antibody, OTTHUMP00000018301 antibody
Immunogen Species
Human
Immunogen
Peptide sequence around phosphorylation site of serine 319 (T-S-S(p)-N-A) derived from Human FKHR/FOXO1A.
Dilution
ELISA:1:2000-1:10000
WB:1:500-1:1000
IHC:1:50-1:100
IF:1:100-1:200
Background

FKHR belongs to the forkhead family of transcription factors, which are characterized by a distinct forkhead domain. It may play a role in myogenic growth and differentiation. The mammalian DAF-16-like transcription factors, FKHR, FKHRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis downstream of phosphoinositide 3-kinase. Gene activation through binding to insulin response sequences has been essential for mediating these functions. D-type Cyclins (in Class III) is required for FKHR mediated inhibition of cell cycle progression and transformation. FKHR gene is mapped to chromosome 13q14

Rena G, et al. (2002) EMBO J 21(9): 2263-2271.
Woods YL, et al. (2001) Biochem J355(Pt 3): 597-607.
Rena G, et al. (2001) Biochem J 354(Pt 3): 605-612.

Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
General Research Areas
Signal Transduction
Initial Research Areas
Signal Transduction
Antigen Species
Human
Antigen
Peptide sequence around phosphorylation site of serine 319 (T-S-S(p)-N-A) derived from Human FKHR/FOXO1A.
Clonality
Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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