FES Antibody

Polyclonal Antibody

FES

c-fes/fps protein antibody, cFES antibody, Feline sarcoma (Snyder Theilen) viral (v fes)/Fujinami avian sarcoma (PRCII) viral (v fps) oncogene homolog antibody, feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami antibody, Feline sarcoma oncogene antibody, Feline sarcoma/Fujinami avian sarcoma oncogene homolog antibody, fes antibody, FES proto oncogene, tyrosine kinase antibody, FES_HUMAN antibody, FPS antibody, Oncogene FES antibody, Oncogene FES feline sarcoma virus antibody, P93c fes antibody, Proto oncogene tyrosine protein kinase Fes/Fps antibody, Proto-oncogene c-Fes antibody, Proto-oncogene c-Fps antibody, proto-oncogene tyrosine-protein kinase Fes/Fps antibody, Tyrosine-protein kinase Fes/Fps antibody

Synthesized peptide derived from internal of human FES.

Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling. Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR. Phosphorylates BCR and down-regulates BCR kinase activity. Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28.

Alcalay M., Oncogene 5:267-275(1990).
Roebroek A.J.M., EMBO J. 4:2897-2903(1985).
Scott A., J. Biomol. NMR 31:357-361(2005).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Signal Transduction

Synthesized peptide derived from internal of Human FES.