NTRK2 (Ab-705) Antibody

Polyclonal Antibody

NTRK2

AI848316 antibody, BDNF tropomyosine receptor kinase B antibody, BDNF/NT 3 growth factors receptor antibody, BDNF/NT-3 growth factors receptor antibody, Brain derived neurotrophic factor receptor antibody, C030027L06Rik antibody, EC 2.7.10.1 antibody, GP145 TrkB antibody, GP145-TrkB antibody, GP145-TrkB/GP95-TrkB antibody, GP95 TrkB antibody, Neurotrophic receptor tyrosine kinase 2 antibody, Neurotrophic tyrosine kinase receptor type 2 antibody, Neurotrophin receptor tyrosine kinase type 2 antibody, NTRK 2 antibody, Ntrk2 antibody, NTRK2_HUMAN antibody, Obesity, hyperphagia, and developmental delay, included antibody, RATTRKB1 antibody, Tkrb antibody, Trk B antibody, Trk-B antibody, TRKB antibody, TrkB tyrosine kinase antibody, TRKB1 antibody, Tropomyosin related kinase B antibody, tyrosine kinase receptor B antibody, Tyrosine receptor kinase B antibody

Peptide sequence around aa.703ca.707 (T-D-Y -Y-R) derived from Human TrkB.

Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.

Woronowicz A, et al. Glycobiology. 2007 Jan, 17(1):10-24. Mojsilovic-Petrovic J, et al. J Neurosci. 2006 Sep 6, 26(36):9250-63. Lewis MA, et al. Mol Pharmacol. 2006 Apr, 69(4):1396-404. Cai D, et al. Physiol Genomics. 2006 Feb 14, 24(3):191-7.

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Human

Polyclonal