Comparison

MLF1 Antibody

Item no. CSB-PA583476
Manufacturer Cusabio
Amount 100 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Hls7 antibody,MLF1 antibody,MLF1_HUMAN antibody,Myelodysplasia myeloid leukemia factor 1 antibody,Myelodysplasia-myeloid leukemia factor 1 antibody,Myeloid leukemia factor 1 antibody,myeloid leukemia factor 1 variant 1 antibody,myeloid leukemia factor 1 variant 2 antibody,myeloid leukemia factor 1 variant 3 antibody
Similar products Myelodysplasia-myeloid leukemia factor 1, Myeloid leukemia factor 1
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
ELISA, WB; WB:1:500-1:3000
Manufacturer - Targets
MLF1
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
Hls7 antibody, MLF1 antibody, MLF1_HUMAN antibody, Myelodysplasia myeloid leukemia factor 1 antibody, Myelodysplasia-myeloid leukemia factor 1 antibody, Myeloid leukemia factor 1 antibody, myeloid leukemia factor 1 variant 1 antibody, myeloid leukemia factor 1 variant 2 antibody, myeloid leukemia factor 1 variant 3 antibody
Immunogen Species
Human
Immunogen
Synthesized peptide derived from internal of human MLF1.
Dilution
ELISA:1:2000-1:10000
WB:1:500-1:3000
Background
Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Yoneda-Kato N., Oncogene 12:265-275(1996) [PubMed: 8570204].
Hanissian S.H., Oncogene 23:3700-3707(2004) [PubMed: 15116101].
Yoneda-Kato N., EMBO J. 24:1739-1749(2005) [PubMed: 15861129].
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
General Research Areas
Cardiovascular
Initial Research Areas
Cardiovascular
Antigen Species
Human
Antigen
Synthesized peptide derived from internal of Human MLF1.
Clonality
Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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