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KLRB1 Antibody (OABF01101-100UL)

KLRB1 Antibody (OABF01101-100UL)

Item no.	OABF01101
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Aging & Neurological Disorders Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Western Blot ELISA Enzymes Fatty Acid Catabolism Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	ELISA
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD161;CLEC5B;C-type lectin domain family 5 member B;hNKR-P1A;killer cell lectin-like receptor subfamily B member 1;killer cell lectin-like receptor subfamily B,member 1;natural killer cell surface protein P1A;NKR;NKR-P1;NKRP1A;NKR-P1A.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	WB: 1:100~1000 IHC-P: 1:100~500 Fluorescent-IHC: 1:50~200
Gene symbol	KLRB1
Gene Fullname	killer cell lectin like receptor B1
Product format	Liquid. Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Reconstitution and storage	-20°C
Description of target	Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1, 3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells.
Protein name	Killer cell lectin-like receptor subfamily B member 1
Clonality	Polyclonal
Purification	Protein A Purified
Immunogen	KLH conjugated synthetic peptide derived from human CD161/NK11
Concentration	1 ug/ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OABF01101-datasheet.pdf

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Amount: 100 ul

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Delivery expected until 12/25/2025

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