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TRP1 Antibody [TYRR1-1]

TRP1 Antibody [TYRR1-1]

Item no.	PRS-34-001-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Oncology Antibodies Immunohistochemistry Immunofluorescence Primary Antibodies By Organ Lung Cancer Testicular & Prostate Cancer
Type	Antibody Monoclonal
Format	Liquid
Applications	IF, IHC-P
Clone	TYRR1-1
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG2a Kappa
Conjugate/Tag	Unconjugated
NCBI	TYRP1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	6-dihydroxyindole-2-carboxylic acid oxidase,DHICA oxidase,11418-,Catalase B,Glycoprotein 75,Melanoma antigen gp75,Tyrosinase-related protein 1,TRP,TRP-1,TRP1,TYRP1,CAS2,TYRP,TYRRP
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Cancer, Cell Cycle, Obesity, Signal Transduction
Background	Tyrosinase-Related Protein-1/TYRP1/TRP1 is a melanocyte-specific gene product involved in melanin synthesis. While mouse Tyrp1 possesses dihydroxyindole carboxylic acid oxidase activity, the function in human melanocytes is less clear. In addition to its role in melanin synthesis, Tyrp1 is involved in stabilizing of tyrosinase protein and modulating its catalytic activity. Tyrp1 is also involved in maintenance of melanosome structure and affects melanocyte proliferation and melanocyte cell death. [Wiki]
By Type	Cancer, Cell Cycle, Obesity, Signal Transduction
Modifications	None
Purification	Protein G affinity chromatography
Concentration	0.2 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	Immunofluorescence: 3-6 ug/ml Immunohistochemistry (FFPE): 3-6 ug/ml for 30 min at RT (1) Prediluted format: incubate for 30 min at RT (2) Titering of the TRP1 antibody may be required for optimal performance. 1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min. 2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Immunogen	Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.
Clonality	Monoclonal
NCBI Official Name	tyrosinase-related protein 1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/4/2025

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