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PIAS4 (Human) cDNA (1ug)

PIAS4 (Human) cDNA (1ug)

Item no.	ANA11780
Manufacturer	AVIVA Systems Biology
Amount	1 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Neural Mitochondrial Function Neural Transcription Factors Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding By Organ Lung Cancer Glial Cell Markers Nucleic Acids DNA cDNA
Type	cDNA
Specific against	other
ECLASS 10.1	32160414
ECLASS 11.0	32160414
UNSPSC	41105324
Similar products	PIAS4
Available
Description	The ORF of human PIAS4 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-PIAS4 polyclonal antibody.
Gene symbol	PIAS4
Description of target	Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Promotes PARK7 sumoylation. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations.
Nucleotide accession_num	NM_015897.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 ug

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Delivery expected until 12/11/2025

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