Comparison

Recombinant Human Bone morphogenetic protein 2 (BMP2) (Active)

Manufacturer Biomatik
Category
Type Proteins Recombinant
Specific against Human
Amount 1mg
Item no. BM-RPC26845-1mg
eClass 6.1 34160400
eClass 9.0 42020190
Available
Gene Name
BMP2
Alternative Names
Bone Morphogenetic Protein 2, BMP-2, Bone Morphogenetic Protein 2A, BMP-2A, BMP2, BMP2A
Uniprot
P12643
Source
E.coli
Expression Region
283-396aa
AA Sequence
QAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAP PGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSV NSKIPKACCVPTELSAISMLYLDENEKVVLKNYQD MVVEGCGCR
Sequence Info
Full Length of Mature Protein
Tag Info
Tag-Free
Theoretical MW
13.3 kDa
Purity
>95% as determined by SDS-PAGE.
Storage Buffer
Lyophilized from a 0.2 um Filtered 10 mM NH4-HAC, pH 4.0
Endotoxin Level
Less than 1.0 EU/ug as determined by LAL method.
Biological Activity
The ED50 as determined by the cytolysis of MC3T3-E1 cells is less than 2 ug/ml
Shipping Condition
Ice packs
Storage
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date
1 year
Restriction
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance
Bone Morphogenetic Protein-2 (BMP-2) is one of the bone-growth regulatory factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of proteins. BMPs are synthesized as large precursor molecules, which are cleaved by proteolytic enzymes. The active form of BMP-2 can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.
Function
Induces cartilage and bone formation
Subcellular location
Secreted
Protein Families
TGF-beta family
Tissue Specificity
Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
Paythway
Hipposignalingpathway

Note: The presented information and documents (Manual, Product Datasheet and Safety Datasheet) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 1mg
Available: In stock
available
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