« Back
Home /
Anti-Phospho-Caveolin-1 (Y14) CAV1 Antibody

Anti-Phospho-Caveolin-1 (Y14) CAV1 Antibody

Item no.	BOS-A00179Y14
Manufacturer	Boster
Amount	100 ul
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Western Blot ELISA Lipid & Fatty Acid Transport Immunostaining
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Alias	Caveolin-1,CAV1,CAV
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	20472 MW
Clonality	Polyclonal
Application Details	WB 1:500-1:2000 ELISA 1:20000
Gene Name	CAV1
Gene Full Name	Caveolin-1
Immunogen	The antiserum was produced against synthesized peptide derived from human Caveolin-1 around the phosphorylation site of Tyr14. AA range:5-54
Contents	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Protein Name	Caveolin-1
Protein Function	May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (PubMed:25893292). Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (PubMed:19262564).
Subcellular Localization	Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola
Description	Boster Bio Anti-Phospho-Caveolin-1 (Y14) CAV1 Antibody catalog # A00179Y14. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Skeletal muscle, liver, stomach, lung, kidney and heart (at protein level). Expressed in the brain.
Short Description	Boster Bio Anti-Phospho-Caveolin-1 (Y14) CAV1 Antibody catalog # A00179Y14. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A00179Y14-datasheet.pdf

BOS-A00179Y14-safety-datasheet.pdf