Anti-GAPDH Antibody (biotin)

Biotin-GAPDH antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Polyclonal

GAPDH

Biotin-GAPDH antibody is human, mouse, rat, rabbit, and chicken reactive.

Biotin-GAPDH antibody was raised against a synthetic peptide containing 16 amino acids near the carboxy terminus of GAPDH.

Biotin-GAPDH antibody is affinity chromatography purified via peptide column.

Signal Transduction, Neuroscience, Homeostasis

Has both glyceraldehyde-3-phosphate dehydrogenase and
nitrosylase activities, thereby playing a role in glycolysis and
nuclear functions, respectively. Participates in nuclear events
including transcription, RNA transport, DNA replication and
apoptosis. Nuclear functions are probably due to the nitrosylase
activity that mediates cysteine S-nitrosylation of nuclear target
proteins such as SIRT1, HDAC2 and PRKDC. Modulates the
organization and assembly of the cytoskeleton. Facilitates the
CHP1-dependent microtubule and membrane associations through its
ability to stimulate the binding of CHP1 to microtubules (By
similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key
enzyme in glycolysis that catalyzes the first step of the pathway
by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-
glyceroyl phosphate. Component of the GAIT (gamma interferon-
activated inhibitor of translation) complex which mediates
interferon-gamma-induced transcript-selective translation
inhibition in inflammation processes. Upon interferon-gamma
treatment assembles into the GAIT complex which binds to stem
loop-containing GAIT elements in the 3'-UTR of diverse
inflammatory mRNAs (such as ceruplasmin) and suppresses their
translation.

Boster Bio Anti-GAPDH Antibody (biotin) (Catalog # A00227-Biotin). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat, Rabbit, Chicken.