« Back
Home /
Anti-PLC Gamma 1 (phospho-Y1253) PLCG1 Antibody

Anti-PLC Gamma 1 (phospho-Y1253) PLCG1 Antibody

Item no.	BOS-A00677Y1253
Manufacturer	Boster
Amount	100 ul
Category	Metabolism Cholesterol & Lipid Metabolism Western Blot Immunocytochemistry Enzymes Other Fatty Acid Enzymes Immunochemistry
Format	Liquid
Applications	WB, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1,3.1.4.11,PLC-148,Phosphoinositide phospholipase C-gamma-1,Phospholipase C-II,PLC-II,Phospholipase C-gamma-1,PLC-gamma-1,PLCG1,PLC1
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	148532 MW
Clonality	Polyclonal
Application Details	WB: 1:500-1:1000 ICC: 1:50-1:200
Gene Name	PLCG1
Gene Full Name	1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-1
Immunogen	Synthetic phosphopeptide derived from human PLC γ1 around the phosphorylation site of Tyrosine 1253.
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-1
Protein Function	Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1, 4, 5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Subcellular Localization	Cell projection, lamellipodium. Cell projection, ruffle. Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.
Description	Boster Bio Anti-PLC Gamma 1 (phospho-Y1253) PLCG1 Antibody catalog # A00677Y1253. Tested in WB, ICC applications. This antibody reacts with Human, Mouse, Rat.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A00677Y1253-datasheet.pdf

BOS-A00677Y1253-safety-datasheet.pdf