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Anti-Growth hormone receptor GHR Antibody

Anti-Growth hormone receptor GHR Antibody

Item no.	BOS-A00698-2
Manufacturer	Boster
Amount	100 ul
Category	Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Flow Cytometry Immunohistochemistry Western Blot Immunocytochemistry Immunochemistry
Format	Liquid
Applications	WB, FC, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Growth hormone receptor,GH receptor,Somatotropin receptor,Growth hormone-binding protein,GH-binding protein,GHBP,Serum-binding protein,GHR
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	71500 MW
Clonality	Polyclonal
Application Details	WB: 1:500 ICC: 1:50-1:200 IHC: 1:50-1:200 FC: 1:50-1:100
Gene Name	GHR
Gene Full Name	Growth hormone receptor
Immunogen	Recombinant protein
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	ProA affinity purified
Concentration	1 mg/ml
Protein Name	Growth hormone receptor
Protein Function	Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity).
Subcellular Localization	Cell membrane; Single-pass type I membrane protein. On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway.
Description	Boster Bio Anti-Growth hormone receptor GHR Antibody catalog # A00698-2. Tested in WB, ICC, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in various tissues with high expression in liver and skeletal muscle. Isoform 4 is predominantly expressed in kidney, bladder, adrenal gland and brain stem. Isoform 1 expression in placenta is predominant in chorion and decidua. Isoform 4 is highly expressed in placental villi. Isoform 2 is expressed in lung, stomach and muscle. Low levels in liver.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A00698-2-datasheet.pdf

BOS-A00698-2-safety-datasheet.pdf