« Back
Home /
Anti-PKC epsilon Monoclonal Antibody

Anti-PKC epsilon Monoclonal Antibody

Item no.	BOS-M01151-30ul
Manufacturer	Boster
Amount	30 ul
Quantity options	100 ul 30 ul
Category	Oncology Metabolism Diabetes Antibodies By Cell Type Melanoma Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, FC, IF, IHC, ICC
Clone	ACDA-16
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<20 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	NF-kappa-B inhibitor alpha,I-kappa-B-alpha,IkB-alpha,IkappaBalpha,Major histocompatibility complex enhancer-binding protein MAD3,NFKBIA,IKBA,MAD3,NFKBI
Available
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	102 kDa
Calculated Molecular weight	35609 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 FC 1:80
Gene Name	PRKCE
Gene Full Name	NF-kappa-B inhibitor alpha
Immunogen	A synthesized peptide derived from human PKC epsilon This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cancer, Cardiovascular, Hypertrophy, Protein Phosphorylation, Ser/Thr Kinases, Serine/Threonine Kinases, Signal Transduction
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Subcellular Localization	Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export.
Description	Boster Bio Anti-PKC epsilon Monoclonal Antibody catalog # M01151. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in brain and skeletal muscle.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M01151-30ul-datasheet.pdf

BOS-M01151-30ul-safety-datasheet.pdf