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Anti-IKB alpha NFKBIA Rabbit Monoclonal Antibody

Anti-IKB alpha NFKBIA Rabbit Monoclonal Antibody

Item no.	BOS-M01139
Manufacturer	Boster
Amount	100 ul
Quantity options	100 ul 30 ul
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IP, IHC, ICC
Clone	HO-14
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<20 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	NF-kappa-B inhibitor alpha,I-kappa-B-alpha,IkB-alpha,IkappaBalpha,Major histocompatibility complex enhancer-binding protein MAD3,NFKBIA,IKBA,MAD3,NFKBI
Available
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	36, 39 kDa
Calculated Molecular weight	35609 MW
Clonality	Monoclonal
Application Details	WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200 IP 1:30
Gene Name	NFKBIA
Gene Full Name	NF-kappa-B inhibitor alpha
Immunogen	A synthesized peptide derived from human IKB alpha
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	0.5mg/ml
Manufacturer - Research Category	Cancer, Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, NFKB Pathway, Nuclear Signaling, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway, TLR Signaling
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Subcellular Localization	Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export.
Description	Boster Bio Anti-IKB alpha NFKBIA Rabbit Monoclonal Antibody catalog # M01139. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in brain and skeletal muscle.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M01139-datasheet.pdf

BOS-M01139-safety-datasheet.pdf