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Anti-IKB epsilon NFKBIE Monoclonal Antibody

Anti-IKB epsilon NFKBIE Monoclonal Antibody

Item no.	BOS-M07073
Manufacturer	Boster
Amount	100 ul
Quantity options	100 ul 30 ul
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Immunochemistry
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IP, IHC, ICC
Clone	ADCF-14
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	<20 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	MAD2L1-binding protein,Caught by MAD2 protein,MAD2L1BP,CMT2,KIAA0110
Available
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	116 kDa
Calculated Molecular weight	31052 MW
Clonality	Monoclonal
Application Details	WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200 IP 1:20
Gene Name	NFKBIE
Gene Full Name	MAD2L1-binding protein
Immunogen	A synthesized peptide derived from human IKB epsilon Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	0.5mg/ml
Manufacturer - Research Category	Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, NFKB Pathway, Nuclear Signaling, Signal Transduction, Signaling Pathway, TLR Signaling, Transcription, Transcription Factors
Protein Name	T-cell surface glycoprotein CD3 zeta chain
Protein Function	May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
Subcellular Localization	Nucleus. Cytoplasm, cytoskeleton, spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
Description	Boster Bio Anti-IKB epsilon NFKBIE Monoclonal Antibody catalog # M07073. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.
Tissue Specificity	Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M07073-datasheet.pdf

BOS-M07073-safety-datasheet.pdf