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Glucokinase Regulator Colorimetric Cell-Based ELISA

Glucokinase Regulator Colorimetric Cell-Based ELISA

Item no.	BOS-EKC1808
Manufacturer	Boster
Amount	1 kit, containing one 96-well plate and all necessary reagents
Category	Metabolism Diabetes ELISA ELISA & Immunoassays ELISA Kits Immunoassay Immunostaining
Type	Elisa-Kit
Applications	ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Glucokinase regulatory protein,GKRP,Glucokinase regulator,GCKR
Available
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Molecular Weight	68685 MW
Gene Name	GCKR
Gene Full Name	Glucokinase regulatory protein
Protein Function	Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
Subcellular Localization	Cytoplasm. Nucleus. Under low glucose concentrations, GKRP associates with GCK and the inactive complex is recruited to the hepatocyte nucleus.
Description	The Glucokinase Regulator Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Glucokinase Regulator protein expression profile in cells. The kit can be used for measuring the relative amounts of Glucokinase Regulator in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Glucokinase Regulator.
Tissue Specificity	Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-EKC1808-datasheet.pdf

BOS-EKC1808-safety-datasheet.pdf