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DKK3 Human, Dickkopf-Related Protein 3 Human Recombinant Protein, HEK

DKK3 Human, Dickkopf-Related Protein 3 Human Recombinant Protein, HEK

Item no.	BOS-PROTQ9UBP4-1
Manufacturer	Boster
Amount	10 ug
Category	Neuroscience Neural Lineage Markers Peptides & Proteins Recombinant Proteins Glial Cell Markers
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Storage Conditions	Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Manufacturer - Format	Lyophilized Powder
Gene Name	DKK3
Purification	Greater than 95% as determined by SDS-PAGE.
Protein Function	Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Tissue Specificity	Highest expression in heart, brain, and spinal cord.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-PROTQ9UBP4-1-datasheet.pdf

BOS-PROTQ9UBP4-1-safety-datasheet.pdf